Sign in or Register   Sign in or Register
  |  

Rabbit Anti-SLC7A11 Recombinant Antibody (D2M7A) (CBMAB-CP2476-LY)

The product is antibody recognizes SLC7A11. The antibody D2M7A immunoassay techniques such as: WB,IP.
See all SLC7A11 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Monkey
Clone
D2M7A
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala224 of human xCT/SLC7A11 protein.
Specificity
Human, Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, pH 7.5, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.4 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Solute Carrier Family 7 Member 11
Introduction
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
Entrez Gene ID
Human23657
Monkey696516
UniProt ID
HumanQ9UPY5
MonkeyF6WP35
Alternative Names
Solute Carrier Family 7 Member 11; Solute Carrier Family 7 (Anionic Amino Acid Transporter Light Chain; Xc- System); Member 11; Calcium Channel Blocker Resistance Protein CCBR1; Amino Acid Transport System Xc-; XCT; Solute Carrier Family 7; (Cationic Amino Acid Transporter; Y+ System) Member 11; Cystine/Glutamate Transporter; CCBR1;
Function
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
Biological Process
Biological Process adult behaviorIEA:Ensembl
Biological Process cellular response to oxidative stressIEA:Ensembl
Biological Process dipeptide import across plasma membraneIEA:Ensembl
Biological Process glutamate homeostasisIEA:Ensembl
Biological Process glutathione metabolic processIEA:Ensembl
Biological Process glutathione transmembrane transportIEA:Ensembl
Biological Process L-glutamate import across plasma membraneIEA:Ensembl
Biological Process lens fiber cell differentiationIEA:Ensembl
Biological Process limb developmentIEA:Ensembl
Biological Process lung alveolus developmentIEA:Ensembl
Biological Process modulation of chemical synaptic transmissionIEA:Ensembl
Biological Process negative regulation of oxidative stress-induced neuron deathIEA:Ensembl
Biological Process platelet aggregationIEA:Ensembl
Biological Process regulation of AMPA glutamate receptor clusteringIEA:Ensembl
Biological Process regulation of cell population proliferationIEA:Ensembl
Biological Process regulation of cysteine metabolic processIEA:Ensembl
Biological Process regulation of glutamate metabolic processIEA:Ensembl
Biological Process regulation of glutathione biosynthetic processIEA:Ensembl
Biological Process regulation of melanin biosynthetic processIEA:Ensembl
Biological Process regulation of neutrophil apoptotic processIEA:Ensembl
Biological Process regulation of protein transportIEA:Ensembl
Biological Process regulation of synapse organizationIEA:Ensembl
Biological Process response to nicotineIEA:Ensembl
Biological Process response to organic cyclic compoundIEA:Ensembl
Biological Process response to redox stateIEA:Ensembl
Biological Process response to toxic substanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process striatum developmentIEA:Ensembl
Biological Process ventricular system developmentIEA:Ensembl
Biological Process visual learningIEA:Ensembl
Cellular Location
Membrane
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-SLC7A11 Recombinant Antibody (D2M7A)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare