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Mouse Anti-SLC8A2 Recombinant Antibody (E-1) (CBMAB-N4292-WJ)

This product is a Mouse antibody that recognizes SLC8A2. The antibody E-1 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SLC8A2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
E-1
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 8 Member A2
Introduction
SLC8A2 (Solute Carrier Family 8 Member A2) is a Protein Coding gene. Among its related pathways are Apelin signaling pathway and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include calmodulin binding and calcium:sodium antiporter activity. An important paralog of this gene is SLC8A3.
Entrez Gene ID
Human6543
Mouse110891
Rat140447
UniProt ID
HumanQ9UPR5
MouseQ8K596
RatP48768
Alternative Names
Solute Carrier Family 8 Member A2; Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 2; Solute Carrier Family 8 Member 2; Na(+)/Ca(2+)-Exchange Protein 2; NCX2; Na+/Ca2+-Exchanging Protein Nac2; Sodium/Calcium Exchanger 2; KIAA1087;
Function
Mediates the electrogenic exchange of Ca2+ against Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes. Contributes to cellular Ca2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca2+ and Na+ excretion.
Biological Process
Biological Process calcium ion export across plasma membraneISS:ARUK-UCL
Biological Process calcium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process calcium ion transmembrane transportISS:UniProtKB
Biological Process cell communicationIEA:InterPro
Biological Process cellular calcium ion homeostasisISS:UniProtKB
Biological Process cognitionISS:ARUK-UCL
Biological Process ion transportTAS:Reactome
Biological Process learningISS:UniProtKB
Biological Process learning or memoryISS:ARUK-UCL
Biological Process long-term synaptic potentiationISS:UniProtKB
Biological Process memoryISS:UniProtKB
Biological Process metal ion transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process modulation of excitatory postsynaptic potentialISS:ARUK-UCL
Biological Process neuron cellular homeostasisISS:ARUK-UCL
Biological Process positive regulation of protein serine/threonine kinase activityISS:ARUK-UCL
Biological Process regulation of action potential firing patternISS:ARUK-UCL
Biological Process regulation of calcineurin-mediated signalingISS:ARUK-UCL
Biological Process regulation of cardiac conductionTAS:Reactome
Biological Process regulation of cytosolic calcium ion concentrationISS:ARUK-UCL
Biological Process regulation of gene expressionISS:ARUK-UCL
Biological Process regulation of short-term neuronal synaptic plasticityISS:UniProtKB
Biological Process response to ischemiaISS:ARUK-UCL
Biological Process sodium ion transmembrane transportISS:UniProtKB
Biological Process synapse organizationISS:ARUK-UCL
Biological Process transport across blood-brain barrier1 PublicationNAS:ARUK-UCL
Cellular Location
Cell membrane
Basolateral cell membrane
Perikaryon
Cell projection, dendrite
Cell projection, dendritic spine
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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