Mouse Anti-SLC9A3R2 Recombinant Antibody (CBXS-4692) (CBMAB-S1926-CQ)

Name: Mouse Anti-SLC9A3R2 Recombinant Antibody (CBXS-4692)
SKU: CBMAB-S1926-CQ
Rating: 5 (1 reviews)

See all SLC9A3R2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-4692

Application

WB, IP

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SLC9A3 Regulator 2

Introduction

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Entrez Gene ID

9351

UniProt ID

Q15599

Alternative Names

SLC9A3 Regulator 2; Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 2; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 3 Regulatory Factor 2; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 3 Regulator 2; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 3 Regulator 2; Solute Carrier Family 9 Isoform A3 Regulatory Factor 2; NHE3 Kinase A Regulatory Protein E3KARP; Tyrosine Kinase Activator Protein 1; SRY-Interacting Protein 1; NHERF-2; NHERF2;

Function

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453).
May also act as scaffold protein in the nucleus.

Biological Process

Biological Process protein localization to plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein-containing complex assemblyManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Endomembrane system
Nucleus
Apical cell membrane
Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity).
Nuclear, in a punctate pattern.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SLC9A3R2 Recombinant Antibody (CBXS-4692)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-SLC9A3R2 Recombinant Antibody (D3A5) (CAT#: CBMAB-N4302-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry