Mouse Anti-SLC9A6 Recombinant Antibody (CBFYM-3129) (CBMAB-M3326-FY)

Name: Mouse Anti-SLC9A6 Recombinant Antibody (CBFYM-3129)
SKU: CBMAB-M3326-FY
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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYM-3129

Application

ELISA, WB, IP

Immunogen

Gel-purified MRSA protein

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 9 (sodium/hydrogen exchanger), member 6

Introduction

This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic cognitive disability, Christianson type. Alternate splicing results in multiple transcript variants.

Entrez Gene ID

10479

UniProt ID

Q92581

Alternative Names

Solute Carrier Family 9 Member A6; Solute Carrier Family 9, Subfamily A (NHE6, Cation Proton Antiporter 6), Member 6; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 6; Na(+)/H(+) Exchanger 6; NHE6; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 6

Function

Electroneutral exchange of protons for Na+ and K+ across the early and recycling endosome membranes. Contributes to calcium homeostasis.

Biological Process

Biological Process axon extensionManual Assertion Based On ExperimentIDA:MGI
Biological Process dendrite extensionManual Assertion Based On ExperimentIDA:MGI
Biological Process ion transportTAS:Reactome
Biological Process neuron projection morphogenesisManual Assertion Based On ExperimentIDA:MGI
Biological Process potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of intracellular pHManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process sodium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Endosome membrane
Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.
Isoform 2
Recycling endosome membrane

Involvement in disease

Intellectual developmental disorder, X-linked, syndromic, Christianson type (MRXSCH):
A syndrome characterized by profound intellectual disability, epilepsy, ataxia, and microcephaly. It shows phenotypic overlap with Angelman syndrome.

PTM

Ubiquitinated (in vitro).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Mouse Anti-SLC9A6 Recombinant Antibody (CBXS-2878) (CAT#: CBMAB-S5628-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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