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Mouse Anti-SLC9A9 Recombinant Antibody (1E10) (CBMAB-A8264-LY)

The product is antibody recognizes SLC9A9. The antibody 1E10 immunoassay techniques such as: WB, ELISA.
See all SLC9A9 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
1E10
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
SLC9A9 (NP_775924.1, 71 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
solute carrier family 9 (sodium/hydrogen exchanger), member 9
Entrez Gene ID
Human285195
Rat363115
UniProt ID
HumanQ8IVB4
RatD4A7H1
Alternative Names
FLJ35613; NHE9; Nbla00118
Function
May act in electroneutral exchange of protons for Na+ across membranes. Involved in the effusion of Golgi luminal H+ in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.
Biological Process
Biological Process ion transportTAS:Reactome
Biological Process potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of intracellular pHManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sodium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Late endosome membrane
Involvement in disease
Autism 16 (AUTS16):
A complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate intellectual disability. AUTS16 can be associated with epilepsy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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