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Rabbit Anti-SLC9A9 Recombinant Antibody (CBXS-1232) (CBMAB-S4094-CQ)

This product is a rabbit antibody that recognizes SLC9A9. The antibody CBXS-1232 can be used for immunoassay techniques such as: WB, IHC-P.
See all SLC9A9 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1232
Antibody Isotype
IgG
Application
WB, IHC-P

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 9 (sodium/hydrogen exchanger), member 9
Introduction
This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder.
Entrez Gene ID
Human285195
Mouse331004
Rat363115
UniProt ID
HumanQ8IVB4
MouseQ8BZ00
RatD4A7H1
Alternative Names
Solute Carrier Family 9 Member A9; Solute Carrier Family 9, Subfamily A (NHE9, Cation Proton Antiporter 9), Member 9; Na(+)/H(+) Exchanger 9; NHE9; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 9; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 9; Solute Carrier Family 9 (Sodium/Hydrogen Exchanger);
Function
May act in electroneutral exchange of protons for Na+ across membranes. Involved in the effusion of Golgi luminal H+ in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.
Biological Process
Biological Process ion transportTAS:Reactome
Biological Process potassium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of intracellular pHManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sodium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Late endosome membrane
Involvement in disease
Autism 16 (AUTS16):
A complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate intellectual disability. AUTS16 can be associated with epilepsy.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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