Rabbit Anti-SLIT1 Recombinant Antibody (CBXS-1219) (CBMAB-S4082-CQ)

Name: Rabbit Anti-SLIT1 Recombinant Antibody (CBXS-1219)
SKU: CBMAB-S4082-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1219

Application

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Slit Guidance Ligand 1

Entrez Gene ID

6585

UniProt ID

O75093

Alternative Names

Slit Guidance Ligand 1; Multiple Epidermal Growth Factor-Like Domains Protein 4; Multiple EGF-Like Domains Protein 4; SLIT-1; SLIL1; MEGF4; Slit (Drosophila) Homolog 1;

Function

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity).
SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Biological Process

Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process dorsal/ventral axon guidanceIEA:Ensembl
Biological Process forebrain morphogenesis1 PublicationNAS:UniProtKB
Biological Process motor neuron axon guidanceManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of axon extension involved in axon guidanceIEA:Ensembl
Biological Process negative regulation of synapse assemblyISS:UniProtKB
Biological Process nuclear migrationIEA:Ensembl
Biological Process retinal ganglion cell axon guidanceIEA:Ensembl
Biological Process spinal cord developmentIEA:Ensembl
Biological Process tangential migration from the subventricular zone to the olfactory bulbIEA:Ensembl

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-SLIT1 Recombinant Antibody (CBXS-1218) (CAT#: CBMAB-S4081-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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