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Rabbit Anti-SLIT1 Recombinant Antibody (CBXS-1219) (CBMAB-S4082-CQ)

This product is a rabbit antibody that recognizes SLIT1. The antibody CBXS-1219 can be used for immunoassay techniques such as: WB.
See all SLIT1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1219
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Slit Guidance Ligand 1
Entrez Gene ID
6585
UniProt ID
O75093
Alternative Names
Slit Guidance Ligand 1; Multiple Epidermal Growth Factor-Like Domains Protein 4; Multiple EGF-Like Domains Protein 4; SLIT-1; SLIL1; MEGF4; Slit (Drosophila) Homolog 1;
Function
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity).
SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Biological Process
Biological Process axon extension involved in axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process axon guidanceManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process dorsal/ventral axon guidanceIEA:Ensembl
Biological Process forebrain morphogenesis1 PublicationNAS:UniProtKB
Biological Process motor neuron axon guidanceManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of axon extension involved in axon guidanceIEA:Ensembl
Biological Process negative regulation of synapse assemblyISS:UniProtKB
Biological Process nuclear migrationIEA:Ensembl
Biological Process retinal ganglion cell axon guidanceIEA:Ensembl
Biological Process spinal cord developmentIEA:Ensembl
Biological Process tangential migration from the subventricular zone to the olfactory bulbIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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