Mouse Anti-SLITRK2 Recombinant Antibody (CBXS-1766) (CBMAB-S4583-CQ)

Name: Mouse Anti-SLITRK2 Recombinant Antibody (CBXS-1766)
SKU: CBMAB-S4583-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-1766

Application

Immunogen

NS0-derived recombinant human SLITRK2, Thr19-Pro617, Accession # Q9H156

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Concentration

LYOPH

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SLIT And NTRK Like Family Member 2

Introduction

This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.

Entrez Gene ID

84631

UniProt ID

Q9H156

Alternative Names

SLIT And NTRK Like Family Member 2; Transmembrane Protein 257; SLITL1; CXorf2; SLIT And NTRK-Like Family, Member 2; Chromosome X Open Reading Frame 1; SLIT And NTRK-Like Protein 2;

Function

It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321).
Suppresses neurite outgrowth (By similarity).

Biological Process

Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of synapse assemblyISS:UniProtKB
Biological Process regulation of presynapse assemblyManual Assertion Based On ExperimentIDA:SynGO
Biological Process regulation of synapse organizationManual Assertion Based On ExperimentIDA:SynGO
Biological Process synaptic membrane adhesionManual Assertion Based On ExperimentIDA:SynGO

Cellular Location

Membrane
Cell membrane

Topology

Extracellular: 22-621
Helical: 622-642
Cytoplasmic: 643-845

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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