Mouse Anti-SLITRK4 Recombinant Antibody (CBXS-1769) (CBMAB-S4586-CQ)

Name: Mouse Anti-SLITRK4 Recombinant Antibody (CBXS-1769)
SKU: CBMAB-S4586-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-1769

Application

Immunogen

NS0-derived recombinant human SLITRK4, Asp19-Pro616, Accession # Q8IW52

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Concentration

LYOPH

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SLIT And NTRK Like Family Member 4

Introduction

This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

139065

UniProt ID

Q8IW52

Alternative Names

SLIT And NTRK Like Family Member 4; SLIT And NTRK-Like Family, Member 4;

Function

It is involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321).
Suppresses neurite outgrowth (By similarity).

Biological Process

Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of presynapse assemblyIEA:InterPro
Biological Process regulation of synapse organizationManual Assertion Based On ExperimentIDA:SynGO

Cellular Location

Membrane
Cell membrane

Topology

Extracellular: 19-618
Helical: 619-639
Cytoplasmic: 640-837

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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