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Mouse Anti-SLITRK4 Recombinant Antibody (CBXS-1769) (CBMAB-S4586-CQ)

This product is a mouse antibody that recognizes SLITRK4. The antibody CBXS-1769 can be used for immunoassay techniques such as: WB.
See all SLITRK4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1769
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
NS0-derived recombinant human SLITRK4, Asp19-Pro616, Accession # Q8IW52
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLIT And NTRK Like Family Member 4
Introduction
This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
139065
UniProt ID
Q8IW52
Alternative Names
SLIT And NTRK Like Family Member 4; SLIT And NTRK-Like Family, Member 4;
Function
It is involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321).
Suppresses neurite outgrowth (By similarity).
Biological Process
Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of presynapse assemblyIEA:InterPro
Biological Process regulation of synapse organizationManual Assertion Based On ExperimentIDA:SynGO
Cellular Location
Membrane
Cell membrane
Topology
Extracellular: 19-618
Helical: 619-639
Cytoplasmic: 640-837
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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