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Mouse Anti-SLITRK5 Recombinant Antibody (CBXS-1764) (CBMAB-S4582-CQ)

This product is a mouse antibody that recognizes SLITRK5. The antibody CBXS-1764 can be used for immunoassay techniques such as: WB.
See all SLITRK5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1764
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
NS0-derived recombinant human SLITRK5, Glu39-Val665, Accession # O94991
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLIT And NTRK Like Family Member 5
Introduction
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).
Entrez Gene ID
26050
UniProt ID
O94991
Alternative Names
SLIT And NTRK Like Family Member 5; Leucine-Rich Repeat-Containing Protein 11; Leucine Rich Repeat Containing 11; LRRC11; SLIT And NTRK-Like Family, Member 5; SLIT And NTRK-Like Protein 5; Slit And Trk Like Gene 5; BA364G4.2; KIAA0918;
Function
Suppresses neurite outgrowth.
Biological Process
Biological Process adult behaviorIEA:Ensembl
Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process chemical synaptic transmissionIEA:Ensembl
Biological Process circulatory system developmentIEA:Ensembl
Biological Process dendrite morphogenesisIEA:Ensembl
Biological Process grooming behaviorIEA:Ensembl
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of presynapse assemblyIEA:InterPro
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process skin developmentIEA:Ensembl
Biological Process striatum developmentIEA:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 41-664
Helical: 665-685
Cytoplasmic: 686-958
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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