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Mouse Anti-SLITRK6 Recombinant Antibody (CBXS-1920) (CBMAB-S4706-CQ)

This product is a mouse antibody that recognizes SLITRK6. The antibody CBXS-1920 can be used for immunoassay techniques such as: ICC.
See all SLITRK6 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1920
Antibody Isotype
IgG2a
Application
ICC

Basic Information

Immunogen
NS0-derived recombinant human SLITRK-6, Ile16-Ala604, Accession # Q9H5Y7
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLIT And NTRK Like Family Member 6
Introduction
This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness.
Entrez Gene ID
84189
UniProt ID
Q9H5Y7
Alternative Names
SLIT And NTRK Like Family Member 6; SLIT And NTRK-Like Family, Member 6; SLIT And NTRK-Like Protein 6; Slit And Trk Like Gene 6; 4832410J21Rik; DFNMYP;
Function
Regulator of neurite outgrowth required for normal hearing and vision.
Biological Process
Biological Process adult locomotory behaviorIEA:Ensembl
Biological Process auditory behaviorIEA:Ensembl
Biological Process auditory receptor cell morphogenesisIEA:Ensembl
Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cochlea developmentIEA:Ensembl
Biological Process innervationIEA:Ensembl
Biological Process lens development in camera-type eyeIEA:Ensembl
Biological Process linear vestibuloocular reflexIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of presynapse assemblyIEA:InterPro
Biological Process sensory perception of soundIEA:UniProtKB-KW
Biological Process startle responseIEA:Ensembl
Biological Process synapse assemblyManual Assertion Based On ExperimentIMP:MGI
Biological Process vestibulocochlear nerve developmentIEA:Ensembl
Biological Process visual perceptionIEA:UniProtKB-KW
Cellular Location
Cell membrane
Involvement in disease
Deafness and myopia (DFNMYP):
An autosomal recessive disorder characterized by prelingual sensorineural hearing loss associated with high myopia.
Topology
Extracellular: 27-608
Helical: 609-629
Cytoplasmic: 630-841
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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