Mouse Anti-SLITRK6 Recombinant Antibody (CBXS-1920) (CBMAB-S4706-CQ)

Name: Mouse Anti-SLITRK6 Recombinant Antibody (CBXS-1920)
SKU: CBMAB-S4706-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-1920

Application

ICC

Immunogen

NS0-derived recombinant human SLITRK-6, Ile16-Ala604, Accession # Q9H5Y7

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SLIT And NTRK Like Family Member 6

Introduction

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness.

Entrez Gene ID

84189

UniProt ID

Q9H5Y7

Alternative Names

SLIT And NTRK Like Family Member 6; SLIT And NTRK-Like Family, Member 6; SLIT And NTRK-Like Protein 6; Slit And Trk Like Gene 6; 4832410J21Rik; DFNMYP;

Function

Regulator of neurite outgrowth required for normal hearing and vision.

Biological Process

Biological Process adult locomotory behaviorIEA:Ensembl
Biological Process auditory behaviorIEA:Ensembl
Biological Process auditory receptor cell morphogenesisIEA:Ensembl
Biological Process axonogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cochlea developmentIEA:Ensembl
Biological Process innervationIEA:Ensembl
Biological Process lens development in camera-type eyeIEA:Ensembl
Biological Process linear vestibuloocular reflexIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process positive regulation of synapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of presynapse assemblyIEA:InterPro
Biological Process sensory perception of soundIEA:UniProtKB-KW
Biological Process startle responseIEA:Ensembl
Biological Process synapse assemblyManual Assertion Based On ExperimentIMP:MGI
Biological Process vestibulocochlear nerve developmentIEA:Ensembl
Biological Process visual perceptionIEA:UniProtKB-KW

Cellular Location

Cell membrane

Involvement in disease

Deafness and myopia (DFNMYP):
An autosomal recessive disorder characterized by prelingual sensorineural hearing loss associated with high myopia.

Topology

Extracellular: 27-608
Helical: 609-629
Cytoplasmic: 630-841

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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