Mouse Anti-SNAP29 Recombinant Antibody (CBXS-3070) (CBMAB-S5816-CQ)

Name: Mouse Anti-SNAP29 Recombinant Antibody (CBXS-3070)
SKU: CBMAB-S5816-CQ
Rating: 5 (1 reviews)

See all SNAP29 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-3070

Application

ELISA, IF, WB

Immunogen

Full length recombinant corresponding to aa1-258 from SNAP29 (AAH09715) with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

synaptosomal-associated protein, 29kDa

Introduction

This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.

Entrez Gene ID

9342

UniProt ID

O95721

Alternative Names

Synaptosome Associated Protein 29; Soluble 29 KDa NSF Attachment Protein; Vesicle-Membrane Fusion Protein SNAP-29; Synaptosomal-Associated Protein, 29kDa; SNAP-29; Synaptosomal-Associated Protein, 29kD; Synaptosome Associated Protein 29kDa; Synaptosomal-Associated Protein 29; CEDNIK;

Function

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions.

Biological Process

Biological Process autophagosome maturationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process autophagosome membrane dockingManual Assertion Based On ExperimentIDA:GO_Central
Biological Process cilium assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process membrane fusionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process protein transportIEA:UniProtKB-KW
Biological Process synaptic vesicle fusion to presynaptic active zone membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process synaptic vesicle primingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle targetingManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cytoplasm
Golgi apparatus membrane
Cytoplasmic vesicle, autophagosome membrane
Cell projection, cilium membrane
Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Localizes to the ciliary pocket from where the cilium protrudes.

Involvement in disease

Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome (CEDNIK):
A neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SNAP29 Recombinant Antibody (CBXS-3070)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-SNAP29 Recombinant Antibody (CBXS-1947) (CAT#: CBMAB-S4726-CQ)

Rabbit Anti-SNAP29 Recombinant Antibody (CBXS-1628) (CAT#: CBMAB-S4477-CQ)

Rabbit Anti-SNAP29 Recombinant Antibody (CBXS-1627) (CAT#: CBMAB-S4476-CQ)

Mouse Anti-SNAP29 Recombinant Antibody (CBXS-2709) (CAT#: CBMAB-S5460-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry