Mouse Anti-SNTB1 Recombinant Antibody (CBXS-3488) (CBMAB-S6218-CQ)

Name: Mouse Anti-SNTB1 Recombinant Antibody (CBXS-3488)
SKU: CBMAB-S6218-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-3488

Application

FC, ICC, IF, IHC, IP, WB

Immunogen

Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane. Epitope: Within the PDZ domain of syntrophin. Cellular Localization: Neuromuscular synapse

Specificity

Dog, Chicken, Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% sodium azide

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Syntrophin Beta 1

Introduction

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

Entrez Gene ID

Human	6641
Mouse	20649
Rat	299940
Chicken	404774
Dog	482030

UniProt ID

Human	Q13884
Mouse	Q99L88
Rat	D3ZWC6
Chicken	Q76EY8
Dog	A0A8I3N5Y8

Alternative Names

Syntrophin Beta 1; Tax Interaction Protein 43; Syntrophin, Beta 1 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 1); 59 KDa Dystrophin-Associated Protein A1 Basic Component 1; Syntrophin-2; SNT2B1; DAPA1B; TIP-43;

Function

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.

Biological Process

Muscle contraction

Cellular Location

Cell membrane, sarcolemma
Cell junction
Cytoplasm, cytoskeleton
In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.

PTM

Phosphorylated by CaM-kinase II.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-SNTB1 Recombinant Antibody (CBXS-3517) (CAT#: CBMAB-S6246-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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