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Mouse Anti-SNTB1 Recombinant Antibody (CBXS-3517) (CBMAB-S6246-CQ)

This product is a mouse antibody that recognizes SNTB1. The antibody CBXS-3517 can be used for immunoassay techniques such as: IHC, WB.
See all SNTB1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rabbit, Rat
Clone
CBXS-3517
Antibody Isotype
IgG1, κ
Application
IHC, WB

Basic Information

Immunogen
Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane (Q13884, NM_021021.3). Cellular Localization: Cell membrane, sarcolemma
Specificity
Human, Mouse, Rabbit, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1 M Tris-Glycine, pH 7.4, 150 mM sodium chloride
Preservative
0.05% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Syntrophin Beta 1
Introduction
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Entrez Gene ID
Human6641
Mouse20649
Rat299940
Rabbit100354514
UniProt ID
HumanQ13884
MouseQ99L88
RatD3ZWC6
RabbitQ28626
Alternative Names
Syntrophin Beta 1; Tax Interaction Protein 43; Syntrophin, Beta 1 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 1); 59 KDa Dystrophin-Associated Protein A1 Basic Component 1; Syntrophin-2; SNT2B1; DAPA1B; TIP-43;
Function
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
Biological Process
Muscle contraction
Cellular Location
Cell membrane, sarcolemma
Cell junction
Cytoplasm, cytoskeleton
In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.
PTM
Phosphorylated by CaM-kinase II.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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