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Mouse Anti-SNX16 Recombinant Antibody (CBXS-2770) (CBMAB-S5521-CQ)

This product is a mouse antibody that recognizes SNX16. The antibody CBXS-2770 can be used for immunoassay techniques such as: ELISA, WB.
See all SNX16 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2770
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa-345 from human SNX16 (AAH33630) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sorting nexin 16
Introduction
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule formation, cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis.
Entrez Gene ID
64089
UniProt ID
P57768
Alternative Names
Sorting Nexin 16;
Function
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
Biological Process
Biological Process early endosome to late endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process endosome to lysosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein targeting to lysosomeManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Early endosome membrane
Late endosome membrane
Cytoplasm
Lysosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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