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Human Anti-SOX1 Recombinant Antibody (CBXS-3569) (CBMAB-S6286-CQ)

This product is a human antibody that recognizes SOX1. The antibody CBXS-3569 can be used for immunoassay techniques such as: FC.
See all SOX1 antibodies

Summary

Host Animal
Human
Specificity
Human
Clone
CBXS-3569
Antibody Isotype
IgG1
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SRY-Box 1
Introduction
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
Entrez Gene ID
6656
UniProt ID
O00570
Alternative Names
SRY-Box 1; SRY (Sex Determining Region Y)-Box 1; SRY-Related HMG-Box Gene 1; SRY Box 1;
Function
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Biological Process
Biological Process anatomical structure morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process chromatin organization1 PublicationNAS:UniProtKB
Biological Process forebrain neuron developmentIEA:Ensembl
Biological Process interneuron migrationISS:UniProtKB
Biological Process lens morphogenesis in camera-type eyeIEA:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IIISS:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of DNA-templated transcriptionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of oligodendrocyte differentiationISS:UniProtKB
Biological Process ventral spinal cord interneuron specificationIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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