Mouse Anti-SP7 Recombinant Antibody (2G6) (CBMAB-A8516-LY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).
Biological Process cementum mineralizationIEA:Ensembl
Biological Process diphosphate metabolic processIEA:Ensembl
Biological Process hematopoietic stem cell differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process osteoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of stem cell differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process regulation of hydrolase activityIEA:Ensembl
Biological Process regulation of transcription by RNA polymerase IIBy SimilarityISS:BHF-UCL
Biological Process response to insulinIEA:Ensembl
Biological Process response to organic cyclic compoundIEA:Ensembl
A form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI12 is an autosomal recessive form characterized by recurrent fractures, mild bone deformations, generalized osteoporosis, delayed teeth eruption, no dentinogenesis imperfecta, normal hearing, and white sclerae.
Propionylated. Depropionylation at Lys-371 by SIRT7 activates transcription factor activity and positively regulates bone formation by osteoblasts.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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