Rabbit Anti-SPON2 Recombinant Antibody (CBXS-1647) (CBMAB-S4496-CQ)

Name: Rabbit Anti-SPON2 Recombinant Antibody (CBXS-1647)
SKU: CBMAB-S4496-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1647

Application

WB, FC

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Spondin 2

Introduction

SPON2 (Spondin 2) is a Protein Coding gene. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include antigen binding and lipopolysaccharide binding. An important paralog of this gene is SPON1.

Entrez Gene ID

Human	10417
Mouse	100689
Rat	171569

UniProt ID

Human	Q9BUD6
Mouse	Q8BMS2
Rat	Q9WV75

Alternative Names

Spondin 2; Mindin; Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1; Spondin 2, Extracellular Matrix Protein; M-Spondin; DIL-1; DIL1; Spondin-2;

Function

Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity).
Binds bacterial lipopolysaccharide (LPS).

Biological Process

Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to lipopolysaccharideIEA:Ensembl
Biological Process defense response to fungusIEA:Ensembl
Biological Process defense response to virusIEA:Ensembl
Biological Process induction of bacterial agglutinationIEA:Ensembl
Biological Process innate immune responseIEA:UniProtKB-KW
Biological Process mast cell mediated immunityIEA:Ensembl
Biological Process opsonizationIEA:Ensembl
Biological Process positive regulation of interleukin-6 productionIEA:Ensembl
Biological Process positive regulation of macrophage cytokine productionIEA:Ensembl
Biological Process positive regulation of tumor necrosis factor productionIEA:Ensembl

Cellular Location

Secreted, extracellular space, extracellular matrix

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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