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Mouse Anti-SRM Recombinant Antibody (CBXS-5777) (CBMAB-S0636-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5777
Antibody Isotype
IgG1
Application
ICC, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
spermidine synthase
Introduction
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
Entrez Gene ID
6723
UniProt ID
P19623
Alternative Names
Spermidine Synthase; Putrescine Aminopropyltransferase; EC 2.5.1.16; SRML1; SPDSY; SPS1; Spermidine Synthase-1; EC 2.5.1; PAPT;
Function
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Biological Process
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process polyamine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermidine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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