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Rabbit Anti-SRP19 Recombinant Antibody (CBXS-1604) (CBMAB-S4453-CQ)

This product is a rabbit antibody that recognizes SRP19. The antibody CBXS-1604 can be used for immunoassay techniques such as: WB, IP, IHC-P, IF.
See all SRP19 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1604
Antibody Isotype
IgG
Application
WB, IP, IHC-P, IF

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Signal Recognition Particle 19
Introduction
SRP19 (Signal Recognition Particle 19) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include 7S RNA binding. An important paralog of this gene is ENSG00000272869.
Entrez Gene ID
Human6728
Mouse66384
Rat291685
UniProt ID
HumanP09132
MouseQ9D7A6
RatB2RZ66
Alternative Names
Signal Recognition Particle 19; Signal Recognition Particle 19kDa;
Function
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).
Binds directly to 7SL RNA (By similarity).
Mediates binding of SRP54 to the SRP complex (By similarity).
Biological Process
Biological Process cotranslational protein targeting to membraneManual Assertion Based On ExperimentTAS:ProtInc
Biological Process SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Nucleus, nucleolus
Nucleus, nucleoplasm
Although the signal recognition particle complex acts in the cytoplasm, it assembles at least in part in the nucleus and/or the nucleolus. SRP19 nuclear import may be mediated by IPO8/Imp8 and TPNO1/Trn.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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