SRP19

SRP19 (Signal Recognition Particle 19) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include 7S RNA binding. An important paralog of this gene is ENSG00000272869.

Full Name

Signal Recognition Particle 19

Function

Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).
Binds directly to 7SL RNA (By similarity).
Mediates binding of SRP54 to the SRP complex (By similarity).

Biological Process

Biological Process cotranslational protein targeting to membraneManual Assertion Based On ExperimentTAS:ProtInc
Biological Process SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Nucleus, nucleolus
Nucleus, nucleoplasm
Although the signal recognition particle complex acts in the cytoplasm, it assembles at least in part in the nucleus and/or the nucleolus. SRP19 nuclear import may be mediated by IPO8/Imp8 and TPNO1/Trn.