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Mouse Anti-SRSF7 Recombinant Antibody (CBLQS-003) (CBMAB-2072CQ)

This product is a mouse monoclonal antibody that recognizes SRSF7. The antibody CBLQS-003 can be used for immunoassay techniques such as: ELISA, WB, ICC, IHC-P.
See all SRSF7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLQS-003
Antibody Isotype
IgG1, Κ
Application
ELISA, WB, ICC, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG1, Κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Serine And Arginine Rich Splicing Factor 7
Introduction
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors.
Entrez Gene ID
6432
UniProt ID
Q16629
Alternative Names
9G8; 35kDa; NX-96; Sfrs7; 9430065L19Rik; serine/arginine-rich splicing factor 7; splicing factor, arginine/serine-rich 7; serine/arginine-rich splicing factor 7; SR splicing factor 7; aging-associated protein 3; splicing factor 9G8; splicing factor, arginine/serine-rich 7, 35kDa
Function
Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
Biological Process
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process mRNA processingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mRNA transportIEA:UniProtKB-KW
Biological Process negative regulation of mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIDA:ProtInc
Cellular Location
Nucleus
Cytoplasm
PTM
Extensively phosphorylated on serine residues in the RS domain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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