Mouse Anti-SRXN1 Recombinant Antibody (CBXS-2275) (CBMAB-S5037-CQ)

Name: Mouse Anti-SRXN1 Recombinant Antibody (CBXS-2275)
SKU: CBMAB-S5037-CQ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBXS-2275

Application

WB, IP, IF, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sulfiredoxin 1

Introduction

SRXN1 (Sulfiredoxin 1) is a Protein Coding gene. Among its related pathways are Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity, acting on a sulfur group of donors and sulfiredoxin activity.

Entrez Gene ID

140809

UniProt ID

Q9BYN0

Alternative Names

Sulfiredoxin 1; C20orf139; SRX1; SRX; Sulfiredoxin 1 Homolog (S. Cerevisiae); Chromosome 20 Open Reading Frame 139; Sulfiredoxin-1; EC 1.8.98.2; Npn3;

Function

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 (PubMed:15448164, PubMed:15590625).
Does not act on PRDX5 or PRDX6 (PubMed:15448164, PubMed:15590625).
May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (PubMed:15448164, PubMed:15590625).

Biological Process

Biological Process cellular response to chemical stressTAS:Reactome
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to oxidative stressManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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