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Mouse Anti-SRXN1 Recombinant Antibody (CBXS-2275) (CBMAB-S5037-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2275
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sulfiredoxin 1
Introduction
SRXN1 (Sulfiredoxin 1) is a Protein Coding gene. Among its related pathways are Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity, acting on a sulfur group of donors and sulfiredoxin activity.
Entrez Gene ID
140809
UniProt ID
Q9BYN0
Alternative Names
Sulfiredoxin 1; C20orf139; SRX1; SRX; Sulfiredoxin 1 Homolog (S. Cerevisiae); Chromosome 20 Open Reading Frame 139; Sulfiredoxin-1; EC 1.8.98.2; Npn3;
Function
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4 (PubMed:15448164, PubMed:15590625).
Does not act on PRDX5 or PRDX6 (PubMed:15448164, PubMed:15590625).
May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (PubMed:15448164, PubMed:15590625).
Biological Process
Biological Process cellular response to chemical stressTAS:Reactome
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to oxidative stressManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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