Rabbit Anti-SSPN Recombinant Antibody (CBXS-1404) (CBMAB-S4262-CQ)

Name: Rabbit Anti-SSPN Recombinant Antibody (CBXS-1404)
SKU: CBMAB-S4262-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1404

Application

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1.051 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sarcospan

Introduction

This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described.

Entrez Gene ID

Human	8082
Mouse	16651
Rat	500364

UniProt ID

Human	Q14714
Mouse	Q62147
Rat	D4ABT9

Alternative Names

Sarcospan; K-Ras Oncogene-Associated Protein; Kirsten-Ras-Associated Protein; KRAG; Sarcospan (Kras Oncogene-Associated Gene); Kras Oncogene-Associated Gene; Kras Oncogene-Associated;

Function

Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.

Biological Process

Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process muscle contractionManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cell membrane
Cell membrane, sarcolemma
Postsynaptic cell membrane
Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions.

Topology

Cytoplasmic: 1-53
Helical: 54-74
Extracellular: 75-86
Helical: 87-107
Cytoplasmic: 108-122
Helical: 123-143
Extracellular: 144-193
Helical: 194-214
Cytoplasmic: 215-243

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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