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Rabbit Anti-SSPN Recombinant Antibody (CBXS-1404) (CBMAB-S4262-CQ)

This product is a rabbit antibody that recognizes SSPN. The antibody CBXS-1404 can be used for immunoassay techniques such as: WB.
See all SSPN antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1404
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1.051 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sarcospan
Introduction
This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described.
Entrez Gene ID
Human8082
Mouse16651
Rat500364
UniProt ID
HumanQ14714
MouseQ62147
RatD4ABT9
Alternative Names
Sarcospan; K-Ras Oncogene-Associated Protein; Kirsten-Ras-Associated Protein; KRAG; Sarcospan (Kras Oncogene-Associated Gene); Kras Oncogene-Associated Gene; Kras Oncogene-Associated;
Function
Component of the dystrophin-glycoprotein complex (DGC), a complex that spans the muscle plasma membrane and forms a link between the F-actin cytoskeleton and the extracellular matrix. Preferentially associates with the sarcoglycan subcomplex of the DGC.
Biological Process
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process muscle contractionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cell membrane
Cell membrane, sarcolemma
Postsynaptic cell membrane
Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions.
Topology
Cytoplasmic: 1-53
Helical: 54-74
Extracellular: 75-86
Helical: 87-107
Cytoplasmic: 108-122
Helical: 123-143
Extracellular: 144-193
Helical: 194-214
Cytoplasmic: 215-243
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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