Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812)


See all SST antibodies
Online Inquiry
Tested Data
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in WB
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in WB
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in FC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in FC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in IHC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in IHC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in IHC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in IHC
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in ELISA
Mouse Anti-SST Recombinant Antibody (CBT4119) (V2LY-0625-LY2812) in ELISA

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4119
Antibody Isotype
IgG1
Application
IHC, FC

Basic Information

Immunogen
Purified recombinant fragment of human SST (AA: 1-116) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
somatostatin
Entrez Gene ID
6750
Research Area
Neuroscience
Function
Somatostatin-14
Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.
Neuronostatin
May enhance low-glucose-induced glucagon release by pancreatic alpha cells (By similarity).
This effect may be mediated by binding to GPR107 and PKA activation (By similarity).
May regulate cardiac contractile function (By similarity).
May compromise cardiomyocyte viability (By similarity).
In the central nervous system, may impair memory retention and may affect hippocampal excitability (By similarity).
May also have anxiolytic and anorexigenic effects (By similarity).
May play a role in arterial pressure regulation (By similarity).
May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (PubMed:29615476).
Biological Process
Cell surface receptor signaling pathway
Cell-cell signaling
Chemical synaptic transmission
Digestion
G protein-coupled receptor signaling pathway
Hormone-mediated apoptotic signaling pathway
Hyperosmotic response
Negative regulation of cell population proliferation
Regulation of cell migration
Regulation of postsynaptic membrane neurotransmitter receptor levels
Response to acidic pH
Response to amino acid
Response to nutrient
Response to steroid hormone
Response to xenobiotic stimulus
Somatostatin signaling pathway
Cellular Location
Secreted
PTM
C-terminal amidation of the neuronostatin peptide is required for its biological activity, including for the regulation of mean arterial pressure.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SST Recombinant Antibody (CBT4119)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry