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Mouse Anti-ST8SIA6 Recombinant Antibody (CBXS-2181) (CBMAB-S4944-CQ)

This product is a mouse antibody that recognizes ST8SIA6. The antibody CBXS-2181 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all ST8SIA6 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBXS-2181
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 6
Introduction
This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
Human338596
Mouse241230
Rat291325
UniProt ID
HumanP61647
MouseQ8K4T1
RatQ6ZXC7
Alternative Names
SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI; ST8SiaVI
Function
Alpha-2,8-sialyltransferase that prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,36-Gal sequence at the non-reducing end of their carbohydrate groups.
Biological Process
Biological Process blastocyst hatchingIEA:Ensembl
Biological Process carbohydrate biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process ganglioside biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process glycolipid biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process glycoprotein metabolic processBy SimilarityISS:BHF-UCL
Biological Process N-glycan processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process oligosaccharide metabolic processBy SimilarityISS:BHF-UCL
Biological Process protein glycosylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein O-linked glycosylationBy SimilarityISS:BHF-UCL
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-3
Helical: 4-24
Lumenal: 25-398
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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