Mouse Anti-ST8SIA6 Recombinant Antibody (CBXS-2181) (CBMAB-S4944-CQ)

Name: Mouse Anti-ST8SIA6 Recombinant Antibody (CBXS-2181)
SKU: CBMAB-S4944-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-2181

Application

WB, IP, IF, ELISA

Specificity

Mouse, Rat, Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 6

Introduction

This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

Human	338596
Mouse	241230
Rat	291325

UniProt ID

Human	P61647
Mouse	Q8K4T1
Rat	Q6ZXC7

Alternative Names

SIA8F; SIAT8-F; SIAT8F; ST8SIA-VI; ST8SiaVI

Function

Alpha-2,8-sialyltransferase that prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc-alpha-2,36-Gal sequence at the non-reducing end of their carbohydrate groups.

Biological Process

Biological Process blastocyst hatchingIEA:Ensembl
Biological Process carbohydrate biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process ganglioside biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process glycolipid biosynthetic processBy SimilarityISS:BHF-UCL
Biological Process glycoprotein metabolic processBy SimilarityISS:BHF-UCL
Biological Process N-glycan processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process oligosaccharide metabolic processBy SimilarityISS:BHF-UCL
Biological Process protein glycosylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein O-linked glycosylationBy SimilarityISS:BHF-UCL

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-3
Helical: 4-24
Lumenal: 25-398

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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