Rabbit Anti-STARD4 Recombinant Antibody (CBXS-1444) (CBMAB-S4302-CQ)

Name: Rabbit Anti-STARD4 Recombinant Antibody (CBXS-1444)
SKU: CBMAB-S4302-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1444

Application

WB, IF

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

StAR Related Lipid Transfer Domain Containing 4

Introduction

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).

Entrez Gene ID

134429

UniProt ID

Q96DR4

Alternative Names

StAR Related Lipid Transfer Domain Containing 4

Function

Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols.

Biological Process

Biological Process cholesterol importManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process cholesterol transport involved in cholesterol storageManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process intracellular cholesterol transportManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of bile acid biosynthetic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of cholesterol metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL

Cellular Location

cytoplasm
cytoplasmic vesicle
cytosol
endoplasmic reticulum

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-STARD4 Recombinant Antibody (CBXS-1445) (CAT#: CBMAB-S4303-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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