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Rabbit Anti-STARD4 Recombinant Antibody (CBXS-1444) (CBMAB-S4302-CQ)

This product is a rabbit antibody that recognizes STARD4. The antibody CBXS-1444 can be used for immunoassay techniques such as: WB, IF.
See all STARD4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1444
Antibody Isotype
IgG
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
StAR Related Lipid Transfer Domain Containing 4
Introduction
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Entrez Gene ID
UniProt ID
Alternative Names
StAR Related Lipid Transfer Domain Containing 4
Function
Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols.
Biological Process
Biological Process cholesterol importManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process cholesterol transport involved in cholesterol storageManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process intracellular cholesterol transportManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of bile acid biosynthetic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of cholesterol metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
cytoplasm
cytoplasmic vesicle
cytosol
endoplasmic reticulum
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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