Mouse Anti-STC2 Recombinant Antibody (2B11) (CBMAB-A8668-LY)

Name: Mouse Anti-STC2 Recombinant Antibody (2B11)
SKU: CBMAB-A8668-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2B11

Application

WB, ELISA

Immunogen

STC2 (AAH00658, 1 a.a. ~ 302 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human, Rat

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

stanniocalcin 2

Introduction

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq]

Entrez Gene ID

Human	8614
Rat	63878

UniProt ID

Human	O76061
Rat	Q9R0K8

Alternative Names

STC-2; STCRP

Function

Has an anti-hypocalcemic action on calcium and phosphate homeostasis.

Biological Process

Biological Process cellular calcium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to hypoxiaIEA:Ensembl
Biological Process decidualizationIEA:Ensembl
Biological Process embryo implantationIEA:Ensembl
Biological Process endoplasmic reticulum unfolded protein responseIEA:Ensembl
Biological Process negative regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of multicellular organism growthIEA:Ensembl
Biological Process regulation of hormone biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of store-operated calcium entryIEA:Ensembl
Biological Process response to oxidative stressIEA:Ensembl
Biological Process response to peptide hormoneIEA:Ensembl
Biological Process response to vitamin DIEA:Ensembl

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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