STC2

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq]
Full Name
stanniocalcin 2
Function
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
Biological Process
Biological Process cellular calcium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cellular response to hypoxiaIEA:Ensembl
Biological Process decidualizationIEA:Ensembl
Biological Process embryo implantationIEA:Ensembl
Biological Process endoplasmic reticulum unfolded protein responseIEA:Ensembl
Biological Process negative regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of multicellular organism growthIEA:Ensembl
Biological Process regulation of hormone biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of store-operated calcium entryIEA:Ensembl
Biological Process response to oxidative stressIEA:Ensembl
Biological Process response to peptide hormoneIEA:Ensembl
Biological Process response to vitamin DIEA:Ensembl
Cellular Location
Secreted
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Anti-STC2 antibodies

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Mouse Anti-STC2 Recombinant Antibody (CF411) (CBMAB-FT104LY)

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Target: STC2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CF411
Application*: ELISA, WB, IF, IHC
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (2B11) (CBMAB-A8668-LY)

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Target: STC2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: 2B11
Application*: WB, E
Datasheet SDS

Rat Anti-STC2 Recombinant Antibody (CBXS-3397) (CBMAB-S6131-CQ)

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Target: STC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3397
Application*: E, WB
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (CBXS-2992) (CBMAB-S5738-CQ)

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Target: STC2
Host: Mouse
Antibody Isotype: IgA, κ
Specificity: Human
Clone: CBXS-2992
Application*: E, WB
Datasheet SDS

Rat Anti-STC2 Recombinant Antibody (CBXS-1788) (CBMAB-S4604-CQ)

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Target: STC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1788
Application*: WB
Datasheet SDS

Rat Anti-STC2 Recombinant Antibody (CBXS-1787) (CBMAB-S4603-CQ)

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Target: STC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1787
Application*: WB
Datasheet SDS

Rat Anti-STC2 (AA 25-302) Recombinant Antibody (CBXS-0769) (CBMAB-S3697-CQ)

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Target: STC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-0769
Application*: E, WB
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (CBXS-0768) (CBMAB-S3696-CQ)

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Target: STC2
Host: Mouse
Antibody Isotype: IgA, κ
Specificity: Human
Clone: CBXS-0768
Application*: WB
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (CBXS-0767) (CBMAB-S3695-CQ)

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Target: STC2
Host: Mouse
Antibody Isotype: IgA, κ
Specificity: Human
Clone: CBXS-0767
Application*: WB
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (CBXS-4379) (CBMAB-S1622-CQ)

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Target: STC2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: CBXS-4379
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-STC2 Recombinant Antibody (CBXS-5702) (CBMAB-S0570-CQ)

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Target: STC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXS-5702
Application*: E, WB, IH, IF
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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