Rabbit Anti-STK17B Recombinant Antibody (CBYCD-513) (CBMAB-D2253-YC)

Name: Rabbit Anti-STK17B Recombinant Antibody (CBYCD-513)
SKU: CBMAB-D2253-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBYCD-513

Application

ICC, IF, IP, WB

Immunogen

A synthetic peptide corresponding to residues 200-300 a.a. in human DRAK2 was used as an immunogen

Specificity

Human, Mouse

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

serine/threonine kinase 17b (apoptosis-inducing)

Introduction

STK17B has broad expression in bone marrow (RPKM 54.0), lymph node (RPKM 45.0) and 18 other tissues. STK17B phosphorylates myosin light chains and acts as a positive regulator of apoptosis.

Entrez Gene ID

Human	9262
Mouse	98267

UniProt ID

Human	O94768
Mouse	Q8BG48

Alternative Names

DRAK2

Function

Phosphorylates myosin light chains (By similarity).
Acts as a positive regulator of apoptosis.

Biological Process

Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of fibroblast apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein autophosphorylationISS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Nucleus
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Colocalizes with STK17B at the plasma membrane.

PTM

Autophosphorylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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