STK17B
STK17B has broad expression in bone marrow (RPKM 54.0), lymph node (RPKM 45.0) and 18 other tissues. STK17B phosphorylates myosin light chains and acts as a positive regulator of apoptosis.
Full Name
serine/threonine kinase 17b (apoptosis-inducing)
Function
Phosphorylates myosin light chains (By similarity).
Acts as a positive regulator of apoptosis.
Acts as a positive regulator of apoptosis.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of fibroblast apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein autophosphorylationISS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of fibroblast apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein autophosphorylationISS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Colocalizes with STK17B at the plasma membrane.
Cell membrane
Endoplasmic reticulum-Golgi intermediate compartment
Colocalizes with STK17B at the plasma membrane.
PTM
Autophosphorylated.
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Anti-STK17B antibodies
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Target: STK17B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-0784
Application*: E, F, IP, WB
Target: STK17B
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2C3
Application*: E, IF, P, WB
Target: STK17B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBXS-5471
Application*: WB, IP, IC
Target: STK17B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: E.959.6
Application*: F, P, IP, WB
Target: STK17B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 33D7
Application*: WB, IP, P, F
Target: STK17B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBYCD-513
Application*: IC, IF, IP, WB
Target: STK17B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CBYCD-511
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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