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Mouse Anti-STK25 Recombinant Antibody (CBXS-0786) (CBMAB-S3713-CQ)

This product is a mouse antibody that recognizes STK25. The antibody CBXS-0786 can be used for immunoassay techniques such as: IF, ELISA, WB.
See all STK25 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0786
Antibody Isotype
IgG3, κ
Application
IF, ELISA, WB

Basic Information

Immunogen
STK25 (AAH07852, 321 a.a.-426 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STK25
Introduction
This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene.
Entrez Gene ID
10494
UniProt ID
O00506
Alternative Names
SOK1; YSK1
Function
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
Biological Process
Biological Process axonogenesisIEA:Ensembl
Biological Process establishment of Golgi localizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process establishment or maintenance of cell polarityIEA:Ensembl
Biological Process Golgi localizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process Golgi reassemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process intrinsic apoptotic signaling pathway in response to hydrogen peroxideManual Assertion Based On ExperimentIGI:UniProtKB
Biological Process positive regulation of axonogenesisIEA:Ensembl
Biological Process positive regulation of stress-activated MAPK cascadeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to hydrogen peroxideManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Golgi apparatus
Localizes to the Golgi apparatus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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