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Mouse Anti-STMN3 Recombinant Antibody (CBXS-2779) (CBMAB-S5530-CQ)

This product is a mouse antibody that recognizes STMN3. The antibody CBXS-2779 can be used for immunoassay techniques such as: ELISA, WB.
See all STMN3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2779
Antibody Isotype
IgM, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa1-181 from human STMN3 with GST tag
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Ascites fluid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
stathmin 3
Introduction
This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
50861
UniProt ID
Q9NZ72
Alternative Names
SCLIP
Function
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Biological Process
Biological Process blastocyst hatchingIEA:Ensembl
Biological Process cytoplasmic microtubule organizationISS:HGNC-UCL
Biological Process microtubule depolymerizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of Rac protein signal transductionISS:HGNC-UCL
Biological Process nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neuron projection developmentISS:HGNC-UCL
Biological Process regulation of cytoskeleton organizationISS:HGNC-UCL
Biological Process regulation of GTPase activityISS:HGNC-UCL
Biological Process regulation of microtubule polymerization or depolymerizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Golgi apparatus
Cell projection, growth cone
Cell projection, axon
Cytoplasm, cytosol
PTM
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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