Sign in or Register   Sign in or Register
  |  

Mouse Anti-STX5 Recombinant Antibody (CBXS-5726) (CBMAB-S0590-CQ)

This product is a mouse antibody that recognizes STX5. The antibody CBXS-5726 can be used for immunoassay techniques such as: WB, ELISA, IHC-P, IF.
See all STX5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5726
Antibody Isotype
IgG1
Application
WB, ELISA, IHC-P, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Syntaxin 5
Introduction
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Entrez Gene ID
6811
UniProt ID
Q13190
Alternative Names
SED5; STX5A
Function
Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus.
(Microbial infection) Required for the efficient production of infectious virion during human cytomegalovirus infection. Mechanistically, participates in the formation of the cytoplasmic viral assembly compartment where tegument acquisition and envelopment occur.
Biological Process
Biological Process early endosome to Golgi transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process Golgi disassemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of Golgi organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusion with Golgi apparatusIEA:Ensembl
Cellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane
Golgi apparatus membrane
Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae.
Topology
Cytoplasmic: 1-333
Helical: 334-354
Vesicular: 355
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-STX5 Recombinant Antibody (CBXS-5726)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare