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Mouse Anti-STX8 (AA 1-237) Recombinant Antibody (CBXS-0834) (CBMAB-S3758-CQ)

This product is a mouse antibody that recognizes STX8. The antibody CBXS-0834 can be used for immunoassay techniques such as: ELISA, WB.
See all STX8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0834
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-237

Target

Full Name
STX8
Introduction
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
9482
UniProt ID
Q9UNK0
Alternative Names
CARB
Function
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.
Biological Process
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process early endosome to late endosome transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process endosome to lysosome transportIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein localization to plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity).
Topology
Cytoplasmic: 1-215
Helical: 216-232
Vesicular: 233-236
PTM
Ubiquitinated by HECTD3.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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