Sign in or Register   Sign in or Register
  |  

Mouse Anti-STXBP2 Recombinant Antibody (CF416) (CBMAB-FT093LY)

The product is antibody recognizes STXBP2 . The antibody CF416 immunoassay techniques such as: ELISA, WB, IHC.
See all STXBP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CF416
Antibody Isotype
IgG2a
Application
ELISA, WB, IHC

Basic Information

Immunogen
syntaxin binding protein 2
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
syntaxin binding protein 2
Entrez Gene ID
6813
UniProt ID
Q15833
Alternative Names
UNC18B
Function
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
Biological Process
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process leukocyte mediated cytotoxicityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process neurotransmitter secretionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neutrophil degranulationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process regulation of mast cell degranulationISS:UniProtKB
Biological Process vesicle docking involved in exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
azurophil granule
cytolytic granule
cytosol
extracellular exosome
extracellular region
plasma membrane
presynapse
secretory granule
specific granule
tertiary granule
Involvement in disease
Hemophagocytic lymphohistiocytosis, familial, 5, with or without microvillus inclusion disease (FHL5):
A rare, autosomal recessive disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits and ataxia. Some patients may present in early infancy with severe diarrhea, prior to the onset of typical FHL features, whereas others present later in childhood and have a more protracted course without diarrhea. The early-onset diarrhea is due to enteropathy reminiscent of microvillus inclusion disease.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-STXBP2 Recombinant Antibody (CF416)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare