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Mouse Anti-SULT1B1 Recombinant Antibody (CBXS-3186) (CBMAB-S5928-CQ)

This product is a mouse antibody that recognizes SULT1B1. The antibody CBXS-3186 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all SULT1B1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3186
Antibody Isotype
IgM, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa1-100 from human SULT1B1 with GST tag
Specificity
Human
Antibody Isotype
IgM, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Ascites fluid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sulfotransferase Family 1B Member 1
Introduction
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes.
Entrez Gene ID
27284
UniProt ID
O43704
Alternative Names
ST1B1; ST1B2; SULT1B2
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) (PubMed:28084139, PubMed:9443824, PubMed:9463486).
May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system (PubMed:35165440).
Biological Process
Biological Process 3'-phosphoadenosine 5'-phosphosulfate metabolic processManual Assertion Based On ExperimentIDA:CAFA
Biological Process cellular biogenic amine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process epithelial cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process ethanol catabolic processManual Assertion Based On ExperimentIDA:CAFA
Biological Process flavonoid metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process phenol-containing compound metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process sulfationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process thyroid hormone metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process xenobiotic metabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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