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Mouse Anti-SUPV3L1 Recombinant Antibody (CBXS-4286) (CBMAB-S1532-CQ)

This product is a mouse antibody that recognizes SUPV3L1. The antibody CBXS-4286 can be used for immunoassay techniques such as: WB, IHC, IHC-P.
See all SUPV3L1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4286
Antibody Isotype
IgG1
Application
WB, IHC, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Suv3 Like RNA Helicase
Introduction
SUPV3L1 (Suv3 Like RNA Helicase) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding.
Entrez Gene ID
6832
UniProt ID
Q8IYB8
Alternative Names
SUV3
Function
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381).
ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Biological Process
Biological Process DNA duplex unwindingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process DNA recombinationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrial mRNA catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrial mRNA surveillanceManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrial ncRNA surveillanceManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrial RNA 3'-end processingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrial RNA surveillanceManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitochondrion morphogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of cell growthManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of mitochondrial RNA catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process RNA catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus
Mitochondrion matrix
Mitochondrion matrix, mitochondrion nucleoid
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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