Human Anti-SUSD2 Recombinant Antibody (CBXS-3571) (CBMAB-S0386-CQ)

Name: Human Anti-SUSD2 Recombinant Antibody (CBXS-3571)
SKU: CBMAB-S0386-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Human

Clone

CBXS-3571

Application

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sushi Domain Containing 2

Introduction

SUSD2 (Sushi Domain Containing 2) is a Protein Coding gene. Diseases associated with SUSD2 include Breast Cancer. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and polysaccharide binding. An important paralog of this gene is MUC4.May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).

Entrez Gene ID

56241

UniProt ID

Q9UGT4

Alternative Names

BK65A6.2

Function

May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403).
May play a role in breast tumorigenesis (PubMed:23131994).

Biological Process

Biological Process negative regulation of cell cycle G1/S phase transitionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell divisionManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cell membrane
SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.

Topology

Extracellular: 28-785
Helical: 786-806
Cytoplasmic: 807-822

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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