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Mouse Anti-SUSD2 Recombinant Antibody (CBXS-1989) (CBMAB-S4758-CQ)

This product is a mouse antibody that recognizes SUSD2. The antibody CBXS-1989 can be used for immunoassay techniques such as: WB, IHC.
See all SUSD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1989
Antibody Isotype
IgG2b
Application
WB, IHC

Basic Information

Immunogen
Human embryonic kidney cell line HEK293-derived human SUSD2, Met1-Ala785, Accession # Q9UGT4
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sushi Domain Containing 2
Introduction
SUSD2 (Sushi Domain Containing 2) is a Protein Coding gene. Diseases associated with SUSD2 include Breast Cancer. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and polysaccharide binding. An important paralog of this gene is MUC4.May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).
Entrez Gene ID
56241
UniProt ID
Q9UGT4
Alternative Names
BK65A6.2
Function
May be a cytokine receptor for GPR15LG. May be a tumor suppressor; together with GPR15LG has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403).
May play a role in breast tumorigenesis (PubMed:23131994).
Biological Process
Biological Process negative regulation of cell cycle G1/S phase transitionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of cell divisionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane
SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.
Topology
Extracellular: 28-785
Helical: 786-806
Cytoplasmic: 807-822
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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