Mouse Anti-SYAP1 Recombinant Antibody (CBXS-5536) (CBMAB-S2743-CQ)

Name: Mouse Anti-SYAP1 Recombinant Antibody (CBXS-5536)
SKU: CBMAB-S2743-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5536

Application

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Tissue culture supernatant

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SYAP1

Introduction

This protein plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation.

Entrez Gene ID

94056

UniProt ID

Q96A49

Alternative Names

FLJ14495; PRO3113

Function

Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339).

Biological Process

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process cellular response to epidermal growth factor stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to insulin stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to insulin-like growth factor stimulusIMP:UniProtKB1 Publication
Biological Process cellular response to platelet-derived growth factor stimulusIMP:UniProtKB1 Publication
Biological Process positive regulation of fat cell differentiationIMP:UniProtKB1 Publication
Biological Process positive regulation of protein serine/threonine kinase activityIMP:UniProtKB1 Publication
Biological Process regulation of short-term neuronal synaptic plasticityIBA:GO_Central1 Publication
Biological Process TORC2 signalingIMP:UniProtKB1 Publication

Cellular Location

Cytoplasm, perinuclear region
Golgi apparatus
Perikaryon
Cell projection, axon
Cell projection, dendrite
Cell projection, growth cone
Presynaptic cell membrane
Postsynaptic cell membrane
Membrane
Localizes to cholinergic neuromuscular junctions and in actin-rich growth cone regions (By similarity).
Membrane-associated in a epidermal growth factor (EGF)-dependent manner (PubMed:23300339).

PTM

Phosphorylated. Phosphorylation increases in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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