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Rabbit Anti-SYCP1 Recombinant Antibody (CBXS-1230) (CBMAB-S4092-CQ)

This product is a rabbit antibody that recognizes SYCP1. The antibody CBXS-1230 can be used for immunoassay techniques such as: WB, IHC-P.
See all SYCP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1230
Antibody Isotype
IgG
Application
WB, IHC-P

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Synaptonemal complex protein 1
Entrez Gene ID
Human6847
Mouse20957
Rat25276
UniProt ID
HumanQ15431
MouseQ62209
RatQ03410
Alternative Names
CT8; SCP1; SCP-1; HOM-TES-14
Function
Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
Biological Process
Biological Process cell divisionIEA:UniProtKB-KW
Biological Process chiasma assemblyIBA:GO_Central1 Publication
Biological Process homologous chromosome pairing at meiosisISS:UniProtKB
Biological Process lateral element assemblyIBA:GO_Central1 Publication
Biological Process meiotic DNA repair synthesisIBA:GO_Central1 Publication
Biological Process protein homotetramerizationIDA:UniProtKB1 Publication
Biological Process reciprocal meiotic recombinationISS:UniProtKB
Biological Process regulation of protein localizationIEA:Ensembl
Biological Process sperm DNA condensationIEA:Ensembl
Biological Process spermatogenesisTAS:ProtInc1 Publication
Biological Process synaptonemal complex assemblyISS:UniProtKB
Cellular Location
Nucleus
Chromosome
Chromosome, centromere
In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex (By similarity).
Only rarely detected at centromeres during leptotene and zygotene. Detected at centromeres during mid-diplotene, when it is no longer present along chromosome arms. No longer detected at centromeres at later stages of meiosis (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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