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Mouse Anti-SYNGR1 Recombinant Antibody (CBXS-0907) (CBMAB-S3826-CQ)


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Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse, Hamster
Clone
CBXS-0907
Antibody Isotype
IgG1
Application
ICC, IP, ELISA, WB, IHC

Basic Information

Specificity
Human, Rat, Mouse, Hamster
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Synaptogyrin 1
Introduction
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified.
Entrez Gene ID
Human9145
Mouse20972
Rat29205
Hamster101833475
UniProt ID
HumanO43759
MouseO55100
RatQ62876
HamsterA0A1U7QGG4
Alternative Names
Synaptogyrin 1
Function
May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity).
Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Biological Process
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process protein targetingIEA:Ensembl
Biological Process regulated exocytosisISS:UniProtKB
Biological Process regulation of long-term neuronal synaptic plasticityISS:UniProtKB
Biological Process regulation of short-term neuronal synaptic plasticityISS:UniProtKB
Biological Process synaptic vesicle membrane organizationISS:UniProtKB
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Melanosome
Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Topology
Cytoplasmic: 1-23
Helical: 24-44
Lumenal: 45-71
Helical: 72-92
Cytoplasmic: 93-103
Helical: 104-124
Lumenal: 125-148
Helical: 149-169
Cytoplasmic: 170-233
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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