Mouse Anti-SYNPO Recombinant Antibody (CBXS-2500) (CBMAB-S5257-CQ)

Name: Mouse Anti-SYNPO Recombinant Antibody (CBXS-2500)
SKU: CBMAB-S5257-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2500

Application

Immunogen

Isolated rat kidney glomeruli

Specificity

Cattle, Guinea pig, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Synaptopodin

Introduction

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).

Entrez Gene ID

Mouse	104027
Rat	60324
Guinea pig	100728174
Cattle	533531

UniProt ID

Mouse	Q8CC35
Rat	Q9Z327
Guinea pig	A0A286XX54
Cattle	E1BA93

Alternative Names

9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661

Function

Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).

Biological Process

Biological Process modification of dendritic spineIDA:SynGO1 Publication
Biological Process positive regulation of actin filament bundle assemblyISS:UniProtKB1 Publication
Biological Process regulation of stress fiber assemblyISS:UniProtKB
Biological Process spine apparatus assemblyIBA:GO_Central1 Publication

Cellular Location

Cytoplasm, cytoskeleton
Cell junction, tight junction
Perikaryon
Cell projection, dendritic spine
Postsynaptic density
Synapse
Cytoplasm, cytosol
Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.

PTM

O-glycosylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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