SYNPO

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).
Full Name
Synaptopodin
Function
Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).
Biological Process
Biological Process modification of dendritic spineIDA:SynGO1 Publication
Biological Process positive regulation of actin filament bundle assemblyISS:UniProtKB1 Publication
Biological Process regulation of stress fiber assemblyISS:UniProtKB
Biological Process spine apparatus assemblyIBA:GO_Central1 Publication
Cellular Location
Cytoplasm, cytoskeleton
Cell junction, tight junction
Perikaryon
Cell projection, dendritic spine
Postsynaptic density
Synapse
Cytoplasm, cytosol
Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.
PTM
O-glycosylated.
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Anti-SYNPO antibodies

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Human SYNPO ELISA Kit (V2LY-0626-LY4058)

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Target: SYNPO
Sensitivity: 0.025 ng/mL
Detection Range: 0.05-10 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Synpo ELISA Kit (V2LY-0626-LY3107)

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Target: Synpo
Sensitivity: 0.053 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Rat Synpo ELISA Kit (V2LY-0626-LY2694)

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Target: Synpo
Sensitivity: 0.0015 ng/mL
Detection Range: 0.003-0.9 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (G1D4) (CBMAB-S6338-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Pig, Rat, Gerbil, Guinea pig, Cattle
Clone: G1D4
Application*: WB, P, C
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-3549) (CBMAB-S6278-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Guinea pig, Human, Mouse, Rat
Clone: CBXS-3549
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-3298) (CBMAB-S6037-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Guinea pig, Human, Mouse, Rat
Clone: CBXS-3298
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-2500) (CBMAB-S5257-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Guinea pig, Mouse, Rat
Clone: CBXS-2500
Application*: IF
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-2499) (CBMAB-S5256-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Guinea pig, Mouse, Rat
Clone: CBXS-2499
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-1979) (CBMAB-S4749-CQ)

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Target: SYNPO
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1979
Application*: IH
Datasheet SDS

Mouse Anti-SYNPO Recombinant Antibody (CBXS-0910) (CBMAB-S3829-CQ)

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Target: SYNPO
Host: Mouse
Specificity: Human
Clone: CBXS-0910
Application*: WB, IC, P, C, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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