Sign in or Register   Sign in or Register
  |  

Rabbit Anti-SYP Recombinant Antibody (RM258) (CBMAB-BR462LY)

The product is antibody recognizes SYP. The antibody RM258 immunoassay techniques such as: IHC, WB.
See all SYP antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
RM258
Antibody Isotype
IgG
Application
IHC: 1:300-1:500 dilution, WB: 0.1-0.5 μg/ml

Basic Information

Immunogen
A peptide corresponding to the C-terminus of Synaptophysin
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol, 1% BSA
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
synaptophysin
Entrez Gene ID
6855
UniProt ID
P08247
Alternative Names
Synaptophysin;Major synaptic vesicle protein p38;SYP;
Function
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Biological Process
Biological Process cellular response to organic substanceIEA:Ensembl
Biological Process endocytosisISS:UniProtKB
Biological Process regulation of long-term neuronal synaptic plasticityISS:UniProtKB
Biological Process regulation of neuronal synaptic plasticityIBA:GO_Central1 Publication
Biological Process regulation of opioid receptor signaling pathwayISS:UniProtKB
Biological Process regulation of short-term neuronal synaptic plasticityISS:UniProtKB
Biological Process regulation of synaptic vesicle exocytosisIEA:Ensembl
Biological Process synaptic vesicle endocytosisIEA:Ensembl
Biological Process synaptic vesicle maturationNAS:UniProtKB1 Publication
Biological Process synaptic vesicle membrane organizationNAS:UniProtKB1 Publication
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Synapse, synaptosome
Involvement in disease
Intellectual developmental disorder, X-linked 96 (XLID96):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
Topology
Cytoplasmic: 1-25
Helical: 26-49
Vesicular: 50-106
Helical: 107-130
Cytoplasmic: 131-137
Helical: 138-161
Vesicular: 162-199
Helical: 200-223
Cytoplasmic: 224-313
PTM
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
Phosphorylated by SRC.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-SYP Recombinant Antibody (RM258)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare