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Mouse Anti-TACC1 Recombinant Antibody (CBYJT-1767) (CBMAB-T0828-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TACC1 (Transforming Acidic Coiled-Coil Containing Protein 1). The antibody can be used for immunoassay techniques, such as WB, IHC.
See all TACC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1767
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
Full length human recombinant protein of human TACC1 (NP_001116296) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Transforming Acidic Coiled-Coil Containing Protein 1
Introduction
TACC1 may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for TACC1.
Entrez Gene ID
6867
UniProt ID
O75410
Alternative Names
Transforming Acidic Coiled-Coil Containing Protein 1; Gastric Cancer Antigen Ga55; Taxin-1; Transforming, Acidic Coiled-Coil Containing Protein 1; Transforming Acidic Coiled-Coil-Containing Protein 1; KIAA1103; Ga55
Function
Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways (PubMed:20078863).
Might promote the nuclear localization of the receptors (PubMed:20078863).
Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
Biological Process
Biological Process cell divisionIEA:UniProtKB-KW
Biological Process cell population proliferationIBA:GO_Central1 Publication
Biological Process cerebral cortex developmentIBA:GO_Central1 Publication
Biological Process microtubule cytoskeleton organizationIBA:GO_Central1 Publication
Biological Process mitotic spindle organizationIEA:InterPro
PTM
Isoform 1 is heavily phosphorylated; isoform 6 is not.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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