Mouse Anti-TACC1 Recombinant Antibody (CBYJT-1767) (CBMAB-T0828-YJ)

Name: Mouse Anti-TACC1 Recombinant Antibody (CBYJT-1767)
SKU: CBMAB-T0828-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-1767

Application

WB, IHC

Immunogen

Full length human recombinant protein of human TACC1 (NP_001116296) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.3, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Transforming Acidic Coiled-Coil Containing Protein 1

Introduction

TACC1 may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for TACC1.

Entrez Gene ID

6867

UniProt ID

O75410

Alternative Names

Transforming Acidic Coiled-Coil Containing Protein 1; Gastric Cancer Antigen Ga55; Taxin-1; Transforming, Acidic Coiled-Coil Containing Protein 1; Transforming Acidic Coiled-Coil-Containing Protein 1; KIAA1103; Ga55

Function

Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways (PubMed:20078863).
Might promote the nuclear localization of the receptors (PubMed:20078863).
Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.

Biological Process

Biological Process cell divisionIEA:UniProtKB-KW
Biological Process cell population proliferationIBA:GO_Central1 Publication
Biological Process cerebral cortex developmentIBA:GO_Central1 Publication
Biological Process microtubule cytoskeleton organizationIBA:GO_Central1 Publication
Biological Process mitotic spindle organizationIEA:InterPro

PTM

Isoform 1 is heavily phosphorylated; isoform 6 is not.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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