Mouse Anti-TACR2 Recombinant Antibody (CBWJN-1691) (CBMAB-N4330-WJ)

Name: Mouse Anti-TACR2 Recombinant Antibody (CBWJN-1691)
SKU: CBMAB-N4330-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBWJN-1691

Application

WB, ICC, IHC-P, IHC-F, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.02% sodium azide

Concentration

0.5 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Tachykinin Receptor 2

Introduction

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008]

Entrez Gene ID

6865

UniProt ID

P21452

Alternative Names

Tachykinin Receptor 2; Neurokinin A Receptor; NK-2 Receptor; NKNAR; TAC2R; NK-2R;

Function

This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K> neuromedin-K> substance P.

Biological Process

Biological Process intestine smooth muscle contractionIEA:Ensembl
Biological Process muscle contractionTAS:ProtInc1 Publication
Biological Process negative regulation of luteinizing hormone secretionIEA:Ensembl
Biological Process operant conditioningIEA:Ensembl
Biological Process positive regulation of acetylcholine secretion, neurotransmissionIEA:Ensembl
Biological Process positive regulation of flagellated sperm motilityIMP:UniProtKB1 Publication
Biological Process positive regulation of smooth muscle contractionTAS:ProtInc1 Publication
Biological Process positive regulation of uterine smooth muscle contractionIEA:Ensembl
Biological Process positive regulation of vascular permeabilityIEA:Ensembl
Biological Process prolactin secretionIEA:Ensembl
Biological Process response to electrical stimulusIEA:Ensembl
Biological Process tachykinin receptor signaling pathwayTAS:ProtInc1 Publication

Cellular Location

Cell membrane

Topology

Extracellular: 1-32
Helical: 33-56
Cytoplasmic: 57-69
Helical: 70-90
Extracellular: 91-107
Helical: 108-129
Cytoplasmic: 130-149
Helical: 150-170
Extracellular: 171-196
Helical: 197-218
Cytoplasmic: 219-251
Helical: 252-272
Extracellular: 273-290
Helical: 291-310
Cytoplasmic: 311-398

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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