Mouse Anti-TAF9B Recombinant Antibody (3365C4a) (CBMAB-T0973-YJ)

Name: Mouse Anti-TAF9B Recombinant Antibody (3365C4a)
SKU: CBMAB-T0973-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3365C4a

Application

Dot, ICC, WB

Immunogen

TAF9L antibody was raised in mouse using recombinant Human Taf9B Rna Polymerase Ii, Tata Box Binding Protein, (Tbp)-Associated Factor, 31Kda (Taf9B)

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4, 1% BSA

Preservative

0.05% Sodium Azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

TATA-Box Binding Protein Associated Factor 9b

Introduction

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF9B is a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.

Entrez Gene ID

Human	51616
Mouse	407786
Rat	171152

UniProt ID

Human	Q9HBM6
Mouse	Q6NZA9
Rat	Q62880

Alternative Names

TATA-Box Binding Protein Associated Factor 9b; TAF9-Like RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 31kDa; TAF9B RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 31kDa; Transcription-Associated Factor TAFII31L; Neuronal Cell Death-Related Protein 7; TAF9L; DN-7; Transcription Initiation Factor TFIID Subunit 9-Like

Function

Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.

Biological Process

Biological Process DNA-templated transcription initiationIEA:InterPro
Biological Process negative regulation of apoptotic processIMP:BHF-UCL2 Publications
Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIC:BHF-UCL1 Publication
Biological Process negative regulation of transcription by RNA polymerase IIIMP:BHF-UCL1 Publication
Biological Process positive regulation of cell growthIMP:UniProtKB1 Publication
Biological Process protein stabilizationIDA:BHF-UCL1 Publication

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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