Mouse Anti-TANC2 Recombinant Antibody (CBYJT-1937) (CBMAB-T1022-YJ)

Name: Mouse Anti-TANC2 Recombinant Antibody (CBYJT-1937)
SKU: CBMAB-T1022-YJ
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBYJT-1937

Application

WB, IP, IF, ELISA

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2

Introduction

TANC2 (Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2) is a Protein Coding gene. Diseases related to TANC2 include Oral Hairy Leukoplakia. An important paralog of TANC2 is TANC1.

Entrez Gene ID

26115

UniProt ID

Q9HCD6

Alternative Names

Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2; Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Domain-Containing Protein 2; Putative Ankyrin-Repeat Containing Protein; Rolling Pebbles Homolog B (Drosophila); Rolling Pebbles Homolog B; Protein TANC2

Function

Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines.

Biological Process

Biological Process dense core granule cytoskeletal transportISS:UniProtKB
Biological Process regulation of dendritic spine developmentISS:UniProtKB
Biological Process regulation of dendritic spine morphogenesisISS:UniProtKB

Cellular Location

Cell projection, dendritic spine

Involvement in disease

Intellectual developmental disorder with autistic features and language delay, with or without seizures (IDDALDS):
An autosomal dominant neurodevelopmental disorder characterized by global developmental delay, varying degrees of intellectual disability, autism spectrum disorder, and delayed language. Some patients develop seizures.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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