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Mouse Anti-TANC2 Recombinant Antibody (CBYJT-1937) (CBMAB-T1022-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TANC2 (Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2). The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all TANC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1937
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2
Introduction
TANC2 (Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2) is a Protein Coding gene. Diseases related to TANC2 include Oral Hairy Leukoplakia. An important paralog of TANC2 is TANC1.
Entrez Gene ID
26115
UniProt ID
Q9HCD6
Alternative Names
Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Containing 2; Tetratricopeptide Repeat, Ankyrin Repeat And Coiled-Coil Domain-Containing Protein 2; Putative Ankyrin-Repeat Containing Protein; Rolling Pebbles Homolog B (Drosophila); Rolling Pebbles Homolog B; Protein TANC2
Function
Scaffolding protein in the dendritic spines which acts as immobile postsynaptic posts able to recruit KIF1A-driven dense core vesicles to dendritic spines.
Biological Process
Biological Process dense core granule cytoskeletal transportISS:UniProtKB
Biological Process regulation of dendritic spine developmentISS:UniProtKB
Biological Process regulation of dendritic spine morphogenesisISS:UniProtKB
Cellular Location
Cell projection, dendritic spine
Involvement in disease
Intellectual developmental disorder with autistic features and language delay, with or without seizures (IDDALDS):
An autosomal dominant neurodevelopmental disorder characterized by global developmental delay, varying degrees of intellectual disability, autism spectrum disorder, and delayed language. Some patients develop seizures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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